Compensatory evolution
WebJun 1, 2024 · This mitonuclear compensatory coevolution hypothesis proposes that products of the nuclear (N) genome evolve novel features, enabling them to alleviate or nullify the dysfunctions that would otherwise be caused by deleterious alleles in … WebJun 1, 2014 · Here, we review studies on the interface of structural biology and molecular evolution that revealed novel aspects of compensatory evolution. In many cases …
Compensatory evolution
Did you know?
WebNov 11, 2024 · Fig. 4: Compensatory evolution of X-linked genes. a, Median ratios of present-day to ancestral gene expression at the two expression layers for 1:1 orthologous X-linked genes in eutherians for... WebHere, we have identified both resistance and fitness-compensatory mutations in EF-G of S. aureus. Our data suggest that compensatory evolution to reduce the fitness costs associated with antibiotic resistance is a frequent occurrence in the clinical environment. Results Identification of fusidic acid resistance mutations
WebNov 16, 2006 · As a result, what appears to be compensatory evolution may often actually be “pseudocompensatory.” Both theoretical and empirical studies indicate that … WebAug 29, 2011 · Here, by specifically discriminating two distinct types of cis-transcompensation, we show, based on stochastic simulations, that compensatory regulatory evolution under stabilizing selection could reduce heterospecific binding and therefore explain the hypothetical increase in the relative contribution of cis-regulatory …
WebApr 28, 2024 · We conclude that compensatory evolution is a previously unrecognized source of morphological diversity and phenotypic novelties. The role of …
WebJun 1, 2024 · Compensatory evolution following gene loss was rapid and pervasive: 68% of the genotypes reached near wild-type fitness through accumulation of adaptive …
WebOct 30, 2024 · Compensatory evolution thus appears to play a central role in driving large MDR-TB epidemics such as that seen with the Beijing CAO-clade. A particular concern is the high prevalence of mutations conferring resistance to second-line drugs currently included in treatment regimens, among the dominant MDR-MTBC strains. tree that myrrh comes fromWebThis dynamic predicts elevated rates of compensatory evolution of mt-aaRS that interact with mt-tRNAs, relative to aaRS that interact with cyt-tRNAs (cyt-aaRS). We find that mt … tree that makes a forestWebTherefore, repeat copy-number variation and divergence represent a distinct evolutionary mechanism that can rapidly generate genetic variability and is likely to compensate for the relatively low... tree that makes catkins crosswordWebNov 8, 2024 · Experimental evolution under high light conditions revealed that an initially low fitness partner-switched non-native host-symbiont pairing rapidly adapted, gaining fitness equivalent to the... tree that looks like an umbrellaWebOct 30, 2024 · The compensatory mechanism for rifampicin-resistant MTBC-strains is proposed to be associated with structural changes in the RNA-polymerase subunits RpoA, RpoB, and RpoC that increase … tree that makes aspirinWebFeb 18, 2024 · The theory of sexually antagonistic coevolution is based on the Red Queen process (15). In short, when males increase their reproductive success through an adaptation that is simultaneously detrimental to females, it creates selection for a counter-adaptation in females to regain their lost fitness. tree that pandas eatWebAug 26, 2014 · Compensatory Evolution Promotes Genomic Diversification. To investigate the genomic changes underlying compensatory evolution, we re-sequenced the complete genomes of 41 … temp agency near 77021