Cytarabine hepatotoxicity
WebCancer Type: Hematologic, Leukemia - Acute Lymphoblastic (ALL) Intent: Curative Regimen Category: evidence-informed Drugs Used: DOXOrubicin, vinCRIStine, dexamethasone, mercaptopurine, pegaspargase, Show More Funding: ODB - General Benefit ODB - General Benefit New Drug Funding Program Table of Contents DANAFARBERINT … WebDec 22, 2011 · Cytarabine (ara-C) have revealed a cumulative dose-dependent hepatotoxicity. Several case reports have demonstrated direct histologic evidence of a hepatotoxic role for ara-C, expressed as increased ALT levels or as intrahepatic cholestasis.
Cytarabine hepatotoxicity
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WebCytarabine: Supportive Care Checklist PRN salt and soda oral mouth rinse PRN antiemetics Blood or platelet transfusions Acetaminophen every 6 hours as needed for fever 5-HT3 PLUS dexamethasone or NK1RA Prednisolone 1% 2 drops in each eye every 4-6 hours beginning before the first dose of cytarabine and continuing until 48 hours after … WebAra-C. Cytarabine is the generic name for the trade name drug Cytosar-U®. In some cases, health care professionals may use the name Ara-C or arabinosylcytosine when referring to the generic drug name cytarabine. Drug type: Cytarabine is an anti-cancer ("antineoplastic" or "cytotoxic") chemotherapy drug. This medication is classified as an ...
WebJun 1, 2024 · cytarabine, hepatotoxicity, liver failure. 2 Hospital Pharmacy 00(0) residual AML with 40% to 50% blasts. Her notable past medi-cal history includes breast cancer … WebCytarabine Hepatic Renal Yes (renal) Dacarbazine Hepatic Renal Consider (renal) Daunorubicin Hepatic Hepatic Yes (hepatic) ... Imatinib mesylate Hepatic Renal, feces Yes (for hepatotoxicity on treatment) Interferon- Renal Renal No Interleukin-2 Renal Renal No Irinotecan Hepatic Renal, hepatic Yes (hepatic) Ixabepilone Hepatic Yes (hepatic)
WebThis site uses cookies. By continuing to browse this site you are agreeing to our use of cookies. WebJun 1, 2024 · cytarabine, hepatotoxicity, liver failure. 2 Hospital Pharmacy 00(0) residual AML with 40% to 50% blasts. Her notable past medi-cal history includes breast cancer treated with lumpectomy .
WebJun 1, 2024 · The most common adverse effects of cytarabine include myelosuppression, nausea, vomiting, diarrhea, and immune-suppression related infection. 5, 9 There is minimal published literature to establish a definitive link between cytarabine and hepatotoxicity. This is further complicated by the varying dosages of HiDAC.
WebJun 1, 2024 · This topic review will cover the clinical use of high-dose MTX for treatment of malignancy, focusing on the prevention and management of toxicity. Intrathecal use of MTX and clinical use of low-dose and intermediate-dose MTX for both malignant and nonmalignant (eg, rheumatologic) conditions are covered elsewhere. (See appropriate … i put the sing in single lyricsWebJun 1, 2024 · This is further complicated by the varying dosages of HiDAC. As a case in point, our patient suffered severe hepatotoxicity at an empirically reduced dose for her … i put the sing in single songWebGastrointestinal toxicity, anorexia, nausea, vomiting and diarrhea have been reported to occur but are mild to moderate in severity and rarely require hospitalization. • Rarely … i put the sing in single singerWebNeurotoxicity from high-dose cytarabine, a pyrimidine metabolite used in treatment for acute myeloid leukemia, is a known but dose-limiting toxicity which has incidences in up to 14% in patients receiving high doses of the drug. Neurologic symptoms vary but range from somnolence and ataxia to more severe complications such as seizures and even ... i put the stud in bible study sweatshirtWebChemotherapy hepatotoxicity and dose modification in patients with liver disease: Conventional cytotoxic agents …contemporary reports, cytarabine infrequently causes … i put the stud in bible studyi put the sing in single lizzoWebStudy with Quizlet and memorize flashcards containing terms like Methrotrexate, Fluorouracil, Cytarabine and more. 46 terms · Methrotrexate → -Myelosuppression -Increased l…, Fluorouracil → -Coronary vasospasm -Hand-foot…, Cytarabine → -Hepatotoxicity -Neurological…, Gemcitabine → -rash -Flu-like syndrome, Purine … i put the wrong address on my order