Hif 1 alpha uniprot

Author: vehr

August undefined, 2024

WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation … Web結構. 缺氧大部分需要氧氣呼吸的物種，都擁有保守序列HIF-1。其轉錄都有嚴格的調控機制。HIF-1是由一個α亞基和一個β亞基組成的異源蛋白二聚體，而β亞基是一種芳香烃受体核转位子（英语： Aryl hydrocarbon receptor nuclear translocator ）（ARNT）。 HIF-1屬於鹼性螺旋-環-螺旋（bHLH）家族中的PER-ARNT-SIM ...

RCSB PDB - 1LQB: Crystal structure of a hydroxylated HIF-1 alpha ...

WebUnder hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth … WebA fusion protein including amino acids 530 - 825 of the mouse HIF-1 alpha protein [UniProt# Q61221]. Purification Purified by antigen-affinity chromatography Conjugation Unconjugated. RRID AB_625919 Note For laboratory use only. Not for any clinical, therapeutic, or ... earl burgin

UniProt

Web3 de jul. de 2003 · Hypoxia-inducible factor 2-alpha (HIF-2-alpha; HIF2-alpha) Member of PAS protein 2; PAS domain-containing protein 2; Gene names. Name. EPAS1. … WebGene summary (Entrez)i. Useful information about the gene from Entrez. This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a … WebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) with an unmodified (non-hydroxylated) proline residue corresponding to proline 564 in UniProt Q16665. The peptide is not efficiently ubiquitinated by a VHL/Elongin B/Elongin C/CUL2/RBX complex (catalog … earl burg obituary

Anti-HIF-1 alpha antibody [ESEE122] (ab8366) Abcam

RCSB PDB - 3KCY: Factor inhibiting HIF-1 alpha in complex with 8 ...

WebUniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product Validations. None available. … WebHuman HIF-1 alpha ELISA kit (ab275103) is a single-wash 90 min sandwich ELISA designed for the quantitative measurement of Human HIF-1 alpha protein in cell and tissue extracts. It uses our proprietary SimpleStep ELISA® technology. Quantitate Human HIF-1 alpha with 33.39 pg/mL sensitivity. earl burgess woodstock ct obitWebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ... earl burger

"WebUniProt : Q16665; Isotype : Rabbit IgG Clonality : Monoclonal; Price : $185/50μl, $299/100μl Availability : Ship next day Rank: Download datasheet [PDF] : Category. Primary Antibodies; ... HIF-1 alpha Antibody detects endogenous levels of total HIF-1 … " - Hif 1 alpha uniprot

Hif 1 alpha uniprot

RCSB PDB - 4H6J: Identification of Cys 255 in HIF-1 as a novel site …

http://www.abways.com/showproduct.asp?cid=CY5197 Web13 de fev. de 2024 · HIF prolyl hydroxylases are oxygen sensors that regulate the stability of the hypoxia-inducible factors (HIFs) in an oxygen-dependent manner. Aragones et al. (2008) showed that loss of Phd1 expression in knockout mice lowers oxygen consumption in skeletal muscle by reprogramming glucose metabolism from oxidative to more anaerobic …

Did you know?

WebGet better batch-to-batch reproducibility with a recombinant antibody. Anti-HIF-1 alpha antibody [EPR16897] (ab179483) Research with confidence – consistent and reproducible results with every batch. Long-term and scalable supply – powered by recombinant technology for fast production. Success from the first experiment – confirmed ... Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca …

WebHypoxia-inducible factor 1 (HIF-1) is an oxygen-regulated transcriptional activator that plays essential roles in mammalian development, physiology and disease pathogenesis. The HIF-1 alpha subunit is subjected to oxygen-dependent ubiquitination and proteasomal degradation that is mediated by the vo … Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation of proline residues triggers destruction of its alpha-subunit while hydroxylation of Asn (803) in the C-terminal …

WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... WebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ...

http://www.abways.com/showproduct.asp?cid=CY5197

WebIn HeLa cells, the levels of HIF-1 alpha and HIF-1 beta protein and HIF-1 DNA-binding activity increased exponentially as cellular oxygen tension decreased, with maximum values at 0.5% oxygen and half-maximal values at 1.5 to 2% oxygen. HIF-1 alpha and HIF-1 beta (ARNT) mRNAs were detected in all human, mouse, and rat organs assayed and mRNA ... css flexbox flex-directionWebUniProt Annotation. GO Annotation. Cytoplasm 1 publication. Nucleus 2 publications. ... IPR001321 HIF-1_alpha; IPR014887 HIF-1_TAD_C; IPR021537 HIF_alpha-like; More … (Microbial infection) Upon infection by human coronavirus SARS-CoV-2, is … We'd like to inform you that we have updated our Privacy Notice to comply … UniRef - UniProt History - UniProt External Links - UniProt Gostaríamos de exibir a descriçãoaqui, mas o site que você está não nos permite. UniProt Annotation. GO Annotation. Cytoplasm 1 publication. Nucleus 2 … 1 domain 7 PTMs 3 reviewed variants 4 isoforms 32 interactions 1 disease 1 3D … css flexbox formWeb9 de mai. de 2002 · Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex. ... Hypoxia-inducible factor 1 ALPHA: D: 34: N/A: Mutation(s): 1 : UniProt & NIH Common Fund Data Resources: Find proteins for Q16665 (Homo sapiens) Explore Q16665 . Go to UniProtKB: Q16665. PHAROS: Q16665. earl burgessWeb19 de set. de 2012 · Identification of Cys 255 in HIF-1 as a novel site for development of covalent inhibitors of HIF-1 /ARNT PasB domain ... Identification of Cys255 in HIF-1 … earl burgess mdWeb8 de mai. de 2015 · Crystal Structure of the Heterodimeric HIF-1a:ARNT Complex with HRE DNA. Crystal Structure of the Heterodimeric HIF-1a: ... UniProt & NIH Common Fund … earl burns ppcliWeb12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … earl burgess blocksWebMonoclonal Anti-HIF2 alpha antibody produced in mouse. clone GT125, affinity isolated ... UniProt accession no. Q16665. shipped in. wet ice. storage temp. −20°C. Gene ... Hif1a(15251) rat ... Hif1a(29560) Description. General description. Hypoxia-inducible factor-1 (HIF-1) is a 120kD basic helix-loop-helix protein that belongs to the PAS ... earl burnett news anchor